The computational-biology tag has no wiki summary.
1
vote
0answers
51 views
Calculating AIC (in R or any other statistical software)
I am trying to fit the log-log plot of the cumulative distribution of a network to one of three models: Exponential (EXP) ($P(k)\sim e^{-ak}$), Exponentially truncated power law (TRU) ($P(k)\sim ...
6
votes
4answers
496 views
Are open-source codes available to study protein folding?
I would like to test the influence of solvation parameters in implicit solvation models and wonder which codes are freely available as standalone programs for protein folding of small proteins, and ...
1
vote
0answers
47 views
Assembled human ESTs for annotation
I am annotating protein-coding genes in a region of the human genome and am looking for a set of assembled ESTs I can use as evidence for constructing gene models. A quick search of NCBI's SRA shows ...
3
votes
1answer
126 views
Global optimal sequence alignment algorithms
As far as global optimal sequence alignment goes, is the Needleman-Wunsch and Hirschberg's algorithm still state of the art? Or have there been any improvements to these algorithms since they were ...
3
votes
1answer
127 views
Artificial RNA 3D folding
I have a 50-base, artificially created RNA sequence and I would like to obtain its 3D structure.
What software should I use for this purpose?
13
votes
8answers
553 views
Parsing protein structure data in C
My background is in genomics, but I have recently been working with problems related to protein structure. I wrote a few relevant programs in C, building my own PDB file parser from scratch in the ...
