I want to compute $\Delta f/f$ (as explained in this link, reference 1), but I am not able to do integration as I have distinct values and no function to generate the continuous time based values.
I have a $1\times N$ time series data where $N$ is the total number of neuron response for one neuron, one for each millisecond. How do I calculate $\Delta f/f$ for this single neuron? If I do $(f_{i+1} - f_{i})/f_{i}$, it gives me very small values.
References
- Jia, Hongbo, et al. "In vivo two-photon imaging of sensory-evoked dendritic calcium signals in cortical neurons." Nature protocols 6.1 (2011): 28-35. doi:10.1038/nprot.2010.169